Complement receptor 2–mediated targeting of complement inhibitors to sites of complement activation
نویسندگان
چکیده
منابع مشابه
Complement receptor 2-mediated targeting of complement inhibitors to sites of complement activation.
In a strategy to specifically target complement inhibitors to sites of complement activation and disease, recombinant fusion proteins consisting of a complement inhibitor linked to a C3 binding region of complement receptor (CR) 2 were prepared and characterized. Natural ligands for CR2 are C3 breakdown products deposited at sites of complement activation. Fusion proteins were prepared consisti...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 2003
ISSN: 0021-9738
DOI: 10.1172/jci17348